Knowledge
MSDS for Glucose
Identification
Product Name: Glucose
Synonyms: D-Glucose, Dextrose, Grape Sugar, Blood Sugar
Chemical Formula: C6H12O6
CAS Number: 50-99-7
Recommended Use: Food ingredient, laboratory reagent, pharmaceutical excipient
Supplier Information: Refer to product label or purchase order for supplier contact details
Emergency Phone Number: Provided on product label and safety documentation
Hazard Identification
GHS Classification: Substance not classified as hazardous under GHS
Signal Word: None
Pictogram: None
Primary Hazards: Dust may cause temporary respiratory irritation and coughing. Contact with eyes may produce mild irritation. Ingestion of large amounts can elevate blood sugar.
Precautionary Statements: Avoid dust formation, handle with care to minimize spills, wash hands after use.
Composition / Information on Ingredients
Chemical Name: D-Glucose
Percent by Weight: 98–100% (as pure substance)
Impurities or Stabilizing Additives: No significant impurities expected in food or pharmaceutical grade batches
First Aid Measures
Inhalation: Move person to fresh air and monitor breathing. If respiratory upset persists, seek medical attention.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing. If irritation develops, consult a physician.
Eye Contact: Rinse with plenty of water for several minutes, lifting eyelids to flush the area. Get medical attention if redness or irritation continues.
Ingestion: Rinse mouth with water. Seek medical advice for large or symptomatic exposures, especially for persons with diabetes or glucose regulation disorders.
Fire-Fighting Measures
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam. Use methods appropriate for surrounding materials.
Unsuitable Media: High-pressure water jet may spread powders.
Specific Hazards: Dusts can form explosive mixtures with air. Decomposition in fire can generate carbon monoxide and carbon dioxide.
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear to prevent inhalation of fine particles and combustion products.
Special Procedures: Move containers from fire area if it can be accomplished without risk.
Accidental Release Measures
Personal Precautions: Avoid dust formation. Use adequate ventilation and personal protective equipment, such as dust masks and safety goggles, especially in enclosed spaces.
Environmental Precautions: Prevent large quantities from entering drains or waterways due to possible nutrient enrichment and fermentation risk.
Cleanup Methods: Sweep up and collect spilled glucose for reuse or disposal. Wash spill area with water only if the product cannot be recovered. Minimize airborne dust during cleanup.
Handling and Storage
Handling: Minimize dust production. Use in well-ventilated areas. Wash hands after handling, particularly before eating or drinking. Store away from incompatible substances.
Storage: Keep containers tightly closed in cool, dry, and well-ventilated facilities. Protect from exposure to moisture and direct sunlight. Use only corrosion-resistant shelving and avoid situations where excessive moisture could lead to product clumping or degradation.
Incompatible Materials: Strong oxidizers, acids, alkalis.
Exposure Controls and Personal Protection
Occupational Exposure Limits: No OSHA or ACGIH exposure limits for glucose; use general nuisance dust limits (10 mg/m3 [total dust], 3 mg/m3 [respirable]) as benchmarks.
Engineering Controls: Local exhaust ventilation recommended in areas of high dust generation.
Personal Protective Equipment: Safety glasses or chemical goggles, dust mask or particulate respirator (such as N95), gloves for skin protection, protective clothing if significant exposure is expected.
Hygiene Practices: Change contaminated clothing, wash hands and exposed skin before breaks and after handling.
Physical and Chemical Properties
Appearance: White, crystalline powder or granules
Odor: Odorless
Odor Threshold: Not applicable
pH: Approximately 6.5 (solution, 50 g/L)
Melting Point: 146°C (295°F)
Boiling Point: Not applicable (decomposes)
Flash Point: Not relevant
Solubility: Soluble in water
Vapor Pressure: Negligible
Density: About 1.54 g/cm3
Partition Coefficient: -3.24 (log Pow)
Viscosity: Not applicable
Evaporation Rate: Not applicable
Stability and Reactivity
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Not reactive under normal circumstances. Reduces some metal salts in solution.
Hazardous Reactions: Can react with strong oxidizing agents, leading to combustion or degradation.
Conditions to Avoid: Excessive heat, humidity, formation of dust clouds near sparks or open flames.
Incompatible Materials: Strong acids, strong bases, oxidizers.
Hazardous Decomposition Products: Carbon monoxide and carbon dioxide during combustion.
Toxicological Information
Acute Toxicity: Oral LD50 (rat): > 25,000 mg/kg, indicating low acute toxicity.
Irritation: Mild eye and respiratory irritant in sensitive individuals.
Chronic Effects: Long-term exposure in occupational settings can contribute to dust-related respiratory symptoms.
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA.
Other Effects: Ingestion affects blood glucose levels; risk is elevated for people with metabolic disorders like diabetes.
Ecological Information
Ecotoxicity: Not toxic to aquatic or terrestrial life in normal environmental concentrations.
Persistence and Degradability: Readily biodegradable. Rapid breakdown by microorganisms in soil and water.
Bioaccumulation Potential: Does not bioaccumulate.
Mobility in Soil: Highly mobile in groundwater as a soluble substance.
Other Effects: Large releases may cause rapid microbial growth or oxygen depletion in water bodies.
Disposal Considerations
Waste Disposal Methods: Dispose as non-hazardous waste in accordance with local regulations. Use landfill or incineration facilities permitted for general chemical residues.
Container Disposal: Rinse empty containers with water and offer for recycling or disposal according to regional rules.
Special Precautions: Avoid uncontrolled release to environment—high organic loads can unbalance wastewater systems.
Transport Information
UN Number: No UN code assigned for glucose; not regulated as dangerous for transport.
Proper Shipping Name: Glucose
Transport Hazard Class: Not hazardous
Packing Group: None assigned
Environmental Hazards: None
Special Transport Precautions: Protect cargo from moisture and physical damage during transit.
Regulatory Information
TSCA (US): Listed
DSL (Canada): Listed
EU REACH: Pre-registered and exempt in many uses as a natural substance
OSHA Hazards: Not classified as hazardous
WHMIS (Canada): Not controlled
California Prop 65: Not listed
Other Regulations: Approved as a food additive by FDA. Compliant with global pharmacopeia standards including USP, BP, EP for pharmaceutical applications.
