Knowledge
Material Safety Data Sheet (MSDS) — Dextrose Monohydrate
Identification
Product Name: Dextrose Monohydrate
Chemical Name: D-Glucose, Monohydrate
Synonyms: Grape sugar, Corn sugar, D-glucose hydrate
Molecular Formula: C6H12O6·H2O
Molecular Weight: 198.17 g/mol
CAS Number: 77938-63-7
Recommended Use: Used widely in food, pharmaceutical, fermentation, and industrial applications
Supplier Identification: Supplier details, including address, phone number, and emergency contact number, should be printed clearly on containers or shipment documents for direct communication during handling or emergencies.
Hazard Identification
Classification: Not classified as hazardous according to OSHA Hazard Communication Standard 29 CFR 1910.1200
Physical Hazards: Not flammable in solid form, but dust can form explosive mixtures with air
Health Hazards: May cause minor irritation to eyes or respiratory system from dust exposure, not expected to cause health hazards under normal use
Environmental Hazards: No significant hazards for aquatic or terrestrial environments have been reported
Label Elements: No pictogram required, precautionary statements for avoid inhaling dust and preventing eye contact
Precautionary Statements: Use in well-ventilated area, avoid generating dust, wash hands after handling
Composition / Information on Ingredients
Chemical Name: Dextrose Monohydrate
CAS Number: 77938-63-7
Content: 99% or greater
Other Ingredients: Trace water, negligible impurities from standard manufacturing processes
Impurities: No hazardous impurities present at concentrations required for disclosure
First Aid Measures
Inhalation: Remove to fresh air if dust inhaled, seek medical attention if coughing or respiratory discomfort persists
Skin Contact: Wash affected area with water, remove contaminated clothing
Eye Contact: Rinse with plenty of water for several minutes, remove contact lenses, seek medical help if irritation continues
Ingestion: Drink water to aid passage, seek medical advice if large quantities are swallowed or symptoms develop
Most Important Symptoms: Mild irritation of eyes, nose, or throat from dust exposure
Notes for Physician: Treat symptomatically, no delayed or immediate effects expected under normal exposure
Fire-Fighting Measures
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide all effectively control fires involving carbohydrate dust
Unsuitable Extinguishing Media: Avoid using high-pressure water streams which can disperse dust
Specific Hazards: Dust accumulations can become explosive in particular conditions, thermal decomposition may generate carbon oxides
Protective Equipment: Firefighters should use full protective gear including self-contained breathing apparatus
Special Procedures: Contain runoff water, ventilate area after extinguishing the fire, prevent buildup of dust around equipment and storage areas to reduce ignition risk
Accidental Release Measures
Personal Precautions: Avoid breathing dust, use dust mask or respirator if ventilation is inadequate, wear safety goggles
Environmental Precautions: Sweep up material, avoid releasing significant quantities into drains or surface water
Methods for Cleanup: Use non-sparking tools, pick up large spills by dry sweeping or vacuuming with explosion-proof equipment, wash away residue with water, dispose according to local guidelines
Additional Advice: Prevent secondary dust clouds during cleanup efforts, secure area to prevent slipping on spilled powder
Handling and Storage
Handling Recommendations: Handle in well-ventilated areas, minimize dust generation, avoid contact with open flames or ignition sources, avoid eating or drinking while handling
Hygiene Practices: Wash hands after use, avoid rubbing eyes, do not bring contaminated equipment or clothing into clean areas
Storage Condition: Store in tightly sealed, dry containers in well-ventilated rooms, away from direct sunlight, strong acids, oxidizers, and moisture
Incompatible Materials: Strong oxidizing agents, acids, strong bases may cause degradation
Storage Life: Dextrose monohydrate remains stable for several years under recommended conditions
Exposure Controls and Personal Protection
Occupational Exposure Limits: Not established for dextrose, control dust exposure under 10 mg/m3 for particulates not otherwise regulated
Engineering Controls: Local exhaust ventilation or general dilution ventilation to control airborne dust
Personal Protective Equipment: Safety glasses with side shields, dust mask (NIOSH-approved) or respirator, gloves to prevent skin contact
Additional Protection: Protective workwear to limit skin exposure, eye-wash stations available in work areas, clean up and maintain all workplace surfaces regularly
Physical and Chemical Properties
Appearance: White crystalline powder or granules
Odor: Odorless
pH (10% Solution): 4.0–6.5
Melting Point: 83°C with decomposition
Solubility: Highly soluble in water, slightly soluble in ethanol
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Not volatile
Specific Gravity: About 1.54 (water = 1)
Partition Coefficient (n-Octanol/water): Not determined
Flammability: Non-flammable as solid, combustible in powder form when dispersed
Explosion Limits: Dust explosion limits begin at 30–60 g/m3
Stability and Reactivity
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not reactive with most chemicals at room temperature
Conditions to Avoid: Excessive heat, open flames, moisture, incompatible chemical storage
Incompatible Substances: Oxidizing agents, acids, bases
Decomposition Products: Carbon monoxide, carbon dioxide, possible toxic fumes on significant heating
Hazardous Polymerization: Not expected under standard environments
Toxicological Information
Acute Toxicity: LD50 (oral, rat): 25,800 mg/kg, considered very low toxicity
Chronic Toxicity: No known significant effects from repeated low-level exposure, recognized as GRAS (Generally Recognized As Safe) for food use
Skin Corrosion/Irritation: Not expected to cause irritation
Serious Eye Damage/Irritation: Mild transient irritation possible
Respiratory Sensitization: Dust may cause mild, temporary symptoms in sensitive individuals
Carcinogenicity: Not classified as carcinogenic
Mutagenicity and Reproductive Toxicity: Not anticipated based on available data
Other Risks: Overexposure to dust may aggravate existing respiratory conditions such as asthma
Ecological Information
Ecotoxicity: Not expected to cause harm to aquatic or terrestrial life at typical use concentrations
Bioaccumulation: Readily biodegradable, does not concentrate in living organisms
Persistence/Degradability: Rapidly broken down by biological action in the environment, no persistence
Mobility in Soil: High solubility in water may carry into soil, but rapid breakdown and consumption by microorganisms
Other Adverse Effects: No ozone depletion, no significant adverse effect reported in field or laboratory studies
Disposal Considerations
Waste Treatment Methods: Dispose of as non-hazardous organic material in accordance with local, national or federal regulations
Recommended Disposal: Mix with large amounts of water, discharge into drains with plenty of water if allowed, or send to landfill as harmless bulk material
Container Handling: Empty containers can be triple rinsed, recycled, or disposed of as ordinary waste after verifying contents
Avoid: Contaminating natural waterways, exceeding permitted release limits
Transport Information
UN Number: Not regulated for transport as hazardous material
Proper Shipping Name: Dextrose Monohydrate
Hazard Class: Not assigned
Packing Group: Not assigned
Transport Labels: No specific label required
Special Precautions: Prevent container breakage, keep dry to avoid caking, secure loads to prevent shifting and dust release during transit
Other Transport Information: Ship in clean, food-grade containers for food or pharmaceutical use
Regulatory Information
Regulatory Status: Dextrose monohydrate is listed by FDA as Generally Recognized As Safe (GRAS), included on food additive and substance inventories by many national regulatory agencies
US Regulations: Not subject to SARA Title III, CERCLA, or state right-to-know reporting
EU Regulations: Not classified as hazardous under Regulation (EC) No 1272/2008, included in European Pharmacopoeia and food safety listings
OSHA: Not hazardous under OSHA Hazard Communication Standard
International Inventories: Present on TSCA, EINECS, and other major chemical substance control inventories
Labeling Requirements: Container identification, traceability, and batch coding for food/pharma use
