Knowledge
Material Safety Data Sheet for Anhydrous Glucose
Identification
Product Name: Anhydrous Glucose
Chemical Name: D-Glucose, Anhydrous
Synonyms: Dextrose; Corn Sugar Anhydrous; Grape Sugar
CAS Number: 50-99-7
Molecular Formula: C6H12O6
Molecular Weight: 180.16 g/mol
Intended Use: Food additive, pharmaceutical excipient, laboratory reagent
Supplier Details: Contact details of supplier, including emergency phone number
Emergency Contact: Please provide 24-hour emergency telephone contact
Hazard Identification
GHS Classification: Not classified as hazardous under GHS criteria
Hazard Statements: Dust may form explosive mixtures with air; may cause minor irritation to eyes and respiratory tract
Pictograms: None required for this material
Signal Word: None
Precautionary Statements: Avoid dust generation, use with adequate ventilation, keep away from ignition sources
Potential Health Effects: Short-term inhalation can cause coughing and mild throat irritation; contact with eyes might lead to temporary discomfort; ingestion considered safe within usual dietary limits
Composition / Information on Ingredients
Chemical Name: D-Glucose, Anhydrous
CAS Number: 50-99-7
Concentration: ≥ 99%
Impurities: Water ≤ 1.0%, negligible levels of salts or heavy metals as allowed by food or pharmaceutical standards
Form: White crystalline powder or granules
First Aid Measures
Inhalation: Remove person to fresh air, seek medical attention if symptoms persist; coughing may occur if high concentrations of dust are inhaled
Skin Contact: Wash skin thoroughly with soap and water; seek medical advice if irritation develops
Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes; lift eyelids as needed; seek medical attention if irritation continues
Ingestion: Rinse mouth with water; obtain medical attention if large quantities consumed or if feeling unwell
Symptoms: Dust in eyes may cause redness or tearing; inhaled dust can irritate airway temporarily
Fire-Fighting Measures
Flash Point: Not applicable
Auto-ignition Temperature: 410°C (770°F)
Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Specific Hazards: Combustible dust hazard; fine particles can cause dust clouds, which may ignite and explode if exposed to ignition sources
Special Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Fire-fighting Techniques: Use water spray to cool fire-exposed containers; avoid high-pressure water jet that may spread dust
Accidental Release Measures
Personal Precautions: Avoid breathing dust; wear suitable dust mask, gloves, and safety glasses
Environmental Precautions: Prevent product from entering drains or watercourses; sweep up residue carefully
Methods for Clean-up: Use non-sparking tools; collect spill using dry methods, place in suitable containers for disposal
Control of Dust: Minimize generation of airborne dust, ventilate area thoroughly, clean surface with damp cloth after bulk removal
Small Spill Response: Sweep or vacuum up material, dispose of safely
Handling and Storage
Handling: Avoid creating dust, keep containers tightly closed, use only in well-ventilated areas, ground equipment to dissipate static electricity
Storage: Store in cool, dry, and well-ventilated place, keep away from incompatible materials (strong oxidizers), protect from moisture and direct sunlight
Other Precautions: Practice good industrial hygiene, wash hands after handling; avoid inhalation and contact with eyes or skin
Exposure Controls and Personal Protection
Exposure Limits: No specific occupational limits set; general nuisance dust limits apply (10 mg/m³ total dust, 3 mg/m³ respirable dust)
Engineering Controls: Use local exhaust ventilation, maintain adequate general ventilation
Personal Protective Equipment: Wear dust mask or respirator (N95 or equivalent) in dusty environments, use safety glasses or goggles, wear gloves
Hygiene Measures: Wash hands and exposed skin before breaks and after work, remove contaminated clothing and wash before reuse
Physical and Chemical Properties
Appearance: White crystalline powder or granules
Odor: Odorless
Melting Point: 146°C
Boiling Point: Not available
Solubility: Freely soluble in water
pH (50g/L, H2O): 5.0 to 7.0
Bulk Density: 0.8 g/cm³ to 1.0 g/cm³
Partition Coefficient (n-octanol/water): -3.24
Vapor Pressure: Not applicable
Flammability: Combustible as dust
Explosive Properties: Fine dust dispersed in air can form explosive mixtures
Decomposition Temperature: Decomposes above 170°C with production of carbon oxides
Viscosity: Not applicable
Evaporation Rate: Not applicable
Stability and Reactivity
Chemical Stability: Stable under recommended storage conditions
Reactivity: No dangerous reactions known under normal conditions
Conditions to Avoid: Moisture, heat, open flames, sources of ignition, static discharge, strong oxidizers
Hazardous Decomposition: Produces carbon monoxide, carbon dioxide under combustion
Polymerization: Will not occur
Toxicological Information
Acute Toxicity: Oral LD50 (rat): > 25800 mg/kg
Inhalation: May cause temporary respiratory irritation if inhaled as dust
Skin Contact: Not expected to cause irritation under normal conditions
Eye Contact: May cause mild mechanical irritation dry or powdered form
Chronic Effects: No evidence of allergic or chronic toxicity, not classified as carcinogenic
Medical Conditions Aggravated: Individuals with pre-existing respiratory conditions may experience irritation; low glycemic effect in individuals with diabetes if handled in bulk
Ecological Information
Ecotoxicity: Low environmental hazard; readily biodegradable
Mobility: Soluble in water; disperses easily in aquatic environments
Persistence and Degradability: Biodegradable, unlikely to persist in the environment
Bioaccumulation: Not expected to bioaccumulate
Aquatic Toxicity: No significant toxicity to aquatic life at relevant concentrations
Disposal Considerations
Product Disposal: Can usually be disposed of as non-hazardous waste; follow local, regional, and national regulations
Contaminated Packaging: Rinse thoroughly before recycling or disposal; manage packaging as per local requirements
Recommended Methods: Landfill or incineration at licensed facility; avoid disposing bulk quantities in the water system
Transport Information
UN Number: Not regulated
Proper Shipping Name: Not classified as dangerous for transport
Transport Hazard Class: Non-hazardous
Packing Group: Not assigned
Marine Pollutant: No
Special Precautions for User: Avoid creating dust during loading and unloading, keep containers closed and secured during transport
Regulatory Information
Regulatory Status: Generally Recognized As Safe (GRAS) by US FDA for food use; listed in relevant pharmacopeias
Labelling Requirements: No special hazard labelling required
Other Regulations: Complies with food and pharmaceutical regulations in US, EU, and other jurisdictions
TSCA Inventory: Listed
REACH Status: Registered or exempted
Note: End user should consult local, state, and federal regulations for specific restrictions and requirements
